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TitleMicrobial cetearyl alcohol for cosmetic & pharmaceutical applications
Knowhow is available forNovel method for the synthesis of cetearyl alcohol using bioengineered E.coli and glucose as a carbon source.
SummaryComputational methods were used to identify the 3 gene additions and 8 deletions necessary to engineer E.coli for alcohol production. Under controlled conditions of fed-batch cultivation (with glucose as the carbon source), the engineered strains produced more than 12 g/L of cetearyl alcohol with more than 99% purity. Demonstrated at lab scale; 5 L fermenter Patent protected
AdvantagesThe advantages of microbial production of cetearyl alcohol are: (1) Clean, environmentally safe process without use of harmful chemicals or heavy metals as catalysts. (2) minimize dependence and risks of price fluctuations related to palm oil trading dynamics (3) Ease of extraction due to extracellular synthesis of cetearyl alcohol (4) uniform and consistent high quality ceteraryl alcohol


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Scientific/ engineering subject areas Chemical sciences & engineering
Investor interest categories Others
Industries Pharmaceuticals, Bulk Drugs, Formulations ;